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Drug Name | Imatinib |
Trade Name | Gleevec |
Synonyms | CGP-57148B|STI571|Imatinib mesylate |
Drug Descriptions |
Gleevec (imatinib) is a multi-target inhibitor of c-Kit, Pdgfr, and Bcr-Abl (PMID: 12200353). Gleevec (imatinib) is FDA approved for c-KIT positive GIST and dermatofibrosarcoma protuberans, Philadelphia chromosome positive chronic myeloid leukemia, and FIP1L1-PDGFRA positive chronic eosinophilic leukemia (FDA.gov). |
DrugClasses | ABL Inhibitor (pan) 9 BCR-ABL Inhibitor 32 CSF1R Inhibitor 28 KIT Inhibitor 57 PDGFR Inhibitor (Pan) 30 |
CAS Registry Number | 220127-57-1 |
NCIT ID | C1687 |