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Drug Name | 5F11-28Z CAR-T cells |
Trade Name | |
Synonyms | 5F11-28Z T cells|5F11-Ts |
Drug Descriptions |
5F11-28Z CAR-T cells are T-lymphocytes engineered to express a chimeric antigen receptor (CAR) targeting TNFRSF8 (CD30) that contains CD28 hinge, transmembrane, and co-stimulatory domains, and a CD3 activation domain, which may inhibit growth of TNFRSF8 (CD30)-expressing tumor cells (PMID: 33287637). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
5F11-28Z CAR-T cells | 5F11-28Z CAR-T cells | 0 | 1 |