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Therapy Name | 5F11-28Z CAR-T cells |
Synonyms | |
Therapy Description |
5F11-28Z CAR-T cells are T-lymphocytes engineered to express a chimeric antigen receptor (CAR) targeting TNFRSF8 (CD30) that contains CD28 hinge, transmembrane, and co-stimulatory domains, and a CD3 activation domain, which may inhibit growth of TNFRSF8 (CD30)-expressing tumor cells (PMID: 33287637). |