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Drug Name | ZM-PI05 |
Trade Name | |
Synonyms | ZM PI05|ZMPI05 |
Drug Descriptions |
ZM-PI05 is a proteolysis-targeting chimera (PROTAC) targeting PI3K, which potentially degrades Pik3ca and Pik3r1 and inhibits proliferation and tumor growth (PMID: 38986734). |
DrugClasses | PI3K Inhibitor (Pan) 42 |
CAS Registry Number | NA |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Lapatinib + ZM-PI05 | Lapatinib ZM-PI05 | 0 | 0 |
ZM-PI05 | ZM-PI05 | 3 | 0 |