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Drug Name | ESR1 peptide-pulsed DC1 vaccine |
Trade Name | |
Synonyms | Autologous native ESR1-pulsed alternating with mutated ESR1-pulsed DC1 Vaccine |
Drug Descriptions |
ESR1 peptide-pulsed DC1 vaccine comprises autologous dendritic cells pulsed with wild-type ESR1 or mutant ESR1, which are delivered in an alternating manner and potentially induce a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing ESR1 (NCI Drug Dictionary). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C212039 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Elacestrant + ESR1 peptide-pulsed DC1 vaccine | ESR1 peptide-pulsed DC1 vaccine Elacestrant | 0 | 1 |
ESR1 peptide-pulsed DC1 vaccine | ESR1 peptide-pulsed DC1 vaccine | 0 | 0 |