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| Drug Name | Elacestrant |
| Trade Name | Orserdu |
| Synonyms | RAD1901 |
| Drug Descriptions |
Orserdu (elacestrant) is a selective estrogen receptor degrader that down-regulates ER and ER-regulated genes, resulting in anti-tumor activity and may be effective in cells resistant to CDK4/6 inhibitors (PMID: 28473534, PMID: 31852484). Orserdu (elacestrant) is FDA approved for use in postmenopausal women or adult men with ER-positive, ERBB2 (HER2)-negative, ESR1 (ER alpha)-mutated advanced or metastatic breast cancer progressed on endocrine therapy (FDA.gov). |
| DrugClasses | Hormone - Anti-estrogens 31 |
| CAS Registry Number | 722533-56-4 |
| NCIT ID | C120211 |
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