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| Drug Name | KK2269 |
| Trade Name | |
| Synonyms | KK-2269|KK 2269 |
| Drug Descriptions |
KK2269 is a bispecific antibody that targets CD40 expressed on antigen presenting cells (APCs) and EPCAM expressed on tumor cells, resulting in EPCAM-dependent activation of CD40 signaling, which potentially enhances antitumor immune response and delays tumor growth (Cancer Res (2024) 84 (6_Supplement): 5310; Cancer Res (2024) 84 (6_Supplement): 5311). |
| DrugClasses | CD40 Antibody 15 |
| CAS Registry Number | NA |
| NCIT ID | C209758 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Docetaxel + KK2269 | Docetaxel KK2269 | 0 | 1 |
| KK2269 | KK2269 | 0 | 1 |
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