MSGV1-PSCA-8T28Z
Drug Detail
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| Drug Name | MSGV1-PSCA-8T28Z |
| Trade Name | |
| Synonyms | Autologous MSGV1-PSCA-8T28Z gdCAR T-cells |
| Drug Descriptions |
MSGV1-PSCA-8T28Z are autologous gamma delta T-lymphocytes engineered to express a chimeric antigen receptor (CAR) targeting PSCA, containing a CD8 alpha hinge and transmembrane domain, CD28 costimulatory domain, and CD3zeta signaling domain, which potentially induce cytotoxicity against PSCA-expressing tumor cells and inhibit tumor growth (PMID: 37134157). |
| DrugClasses | PSCA Immune Cell Therapy 3 |
| CAS Registry Number | NA |
| NCIT ID | C204025 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| MSGV1-PSCA-8T28Z | MSGV1-PSCA-8T28Z | 0 | 1 |
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