APVO436
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| Drug Name | APVO436 |
| Trade Name | |
| Synonyms | APVO-436|APVO 436|Mipletamig |
| Drug Descriptions |
APVO436 is a T-cell engager comprising a bispecific antibody targeting IL3RA (CD123) on tumor cells and CD3 on T-cells, which potentially induces antitumor immune activity (PMID: 34439266). |
| DrugClasses | CD123 (IL3RA) Antibody 14 CD3 Antibody 119 |
| CAS Registry Number | 2839556-21-5 |
| NCIT ID | C157257 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| APVO436 | APVO436 | 0 | 0 |
| APVO436 + Azacitidine + Venetoclax | APVO436 Azacitidine Venetoclax | 0 | 1 |
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