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| Drug Name | VS-7375 |
| Trade Name | |
| Synonyms | VS 7375|VS7375|GFH 375|GFH-375|GFH375 |
| Drug Descriptions |
VS-7375 (GFH375) selectively inhibits KRAS G12D, which potentially results in decreased cell proliferation and inhibition of tumor growth (Cancer Res (2024) 84 (6_Supplement): 3318). |
| DrugClasses | KRAS G12D Inhibitor 25 |
| CAS Registry Number | NA |
| NCIT ID | NA |
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Carboplatin + Pembrolizumab + Pemetrexed Disodium + VS-7375 | Carboplatin Pembrolizumab Pemetrexed Disodium VS-7375 | 0 | 1 |
| Cetuximab + VS-7375 | Cetuximab VS-7375 | 0 | 1 |
| Gemcitabine + Nab-paclitaxel + VS-7375 | Gemcitabine Nab-paclitaxel VS-7375 | 0 | 1 |
| Gemcitabine + VS-7375 | Gemcitabine VS-7375 | 0 | 1 |
| VS-7375 | VS-7375 | 0 | 1 |