TGFBR2 KO CAR27/IL-15 NK cells
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| Drug Name | TGFBR2 KO CAR27/IL-15 NK cells |
| Trade Name | |
| Synonyms | Allogeneic TGFBR2 KO CAR27/IL-15-expressing NK cells |
| Drug Descriptions |
TGFBR2 KO CAR27/IL-15 NK cells are allogeneic natural killer cells engineered to express a chimeric antigen receptor (CAR) targeting CD70, to express IL-15, and with TGFBR2 deletion, which potentially induce cytotoxicity in tumor cells expressing CD70 (NCI Drug Dictionary). |
| DrugClasses | CD70 Immune Cell Therapy 11 |
| CAS Registry Number | NA |
| NCIT ID | C215857 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| TGFBR2 KO CAR27/IL-15 NK cells | TGFBR2 KO CAR27/IL-15 NK cells | 0 | 1 |
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