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Therapy Name | TGFBR2 KO CAR27/IL-15 NK cells |
Synonyms | |
Therapy Description |
TGFBR2 KO CAR27/IL-15 NK cells are allogeneic natural killer cells engineered to express a chimeric antigen receptor (CAR) targeting CD70, to express IL-15, and with TGFRB2 deletion, which potentially induce cytotoxicity in tumor cells expressing CD70 (NCI Drug Dictionary). |