OPB-101
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| Drug Name | OPB-101 |
| Trade Name | |
| Synonyms | OPB101|OPB 101 |
| Drug Descriptions |
OPB-101 comprises T-lymphocytes engineered to express a chimeric antigen receptor (CAR) targeting MSLN, in addition to a novel promoter, safety switch, and a CD8alpha-targeted IL-2/15 cytokine, which potentially induces killing of MSLN-expressing tumor cells and inhibits tumor growth (Cancer Res (2024) 84 (6_Supplement): 51). |
| DrugClasses | MSLN Immune Cell Therapy 10 |
| CAS Registry Number | NA |
| NCIT ID | NA |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| OPB-101 | OPB-101 | 0 | 1 |
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