AMG 410
Drug Detail
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| Drug Name | AMG 410 |
| Trade Name | |
| Synonyms | AMG410|AMG-410 |
| Drug Descriptions |
AMG 410 inhibits KRAS in both GTP- and GDP-bound states, with activity against KRAS G12D, G12V, and G13D, which potentially decreases Kras signaling and tumor growth (Cancer Res (2025) 85 (8_Supplement_2): ND01). |
| DrugClasses | KRAS G12D Inhibitor 25 KRAS Inhibitor 30 |
| CAS Registry Number | NA |
| NCIT ID | NA |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| AMG 410 | AMG 410 | 0 | 1 |
| AMG 410 + Panitumumab | AMG 410 Panitumumab | 0 | 1 |
| AMG 410 + Pembrolizumab | AMG 410 Pembrolizumab | 0 | 1 |
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