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| Drug Name | B7H3 CAR-T cells |
| Trade Name | |
| Synonyms | |
| Drug Descriptions |
B7H3 CAR-T cells are T-lymphocytes engineered to express a chimeric antigen receptor (CAR) targeting CD276 (B7-H3) linked to a CD137 (4-1BB) co-stimulatory motif and a CD3zeta signaling domain, which potentially inhibit tumor growth (PMID: 30655315, J Clin Oncol 2025 43: 16_suppl, 2018). |
| DrugClasses | CD276 Immune Cell Therapy 10 |
| CAS Registry Number | NA |
| NCIT ID | NA |
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| B7H3 CAR-T cells | B7H3 CAR-T cells | 0 | 2 |