Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Drug Name | CTD402 |
| Trade Name | |
| Synonyms | CTD 402|CTD-402 |
| Drug Descriptions |
CTD402 comprises T-lymphocytes that have been engineered with knockout of CD7, HLA-II, and TCR, and to express a chimeric antigen receptor (CAR) that targets CD7 and contains a 4-1BB co-stimulatory domain, a CD3zeta signaling domain, and a gammaC intracellular domain, which may lead to anti-tumor activity against CD7-expressing tumor cells (HemaSphere 2025; 9 (S1):431-432). |
| DrugClasses | CD7 Immune Cell Therapy 4 |
| CAS Registry Number | NA |
| NCIT ID | C222291 |
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| CTD402 | CTD402 | 0 | 1 |