i15.NKG2D.zeta NK cells
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| Drug Name | i15.NKG2D.zeta NK cells |
| Trade Name | |
| Synonyms | i15.NKG2D.zeta-NK cells |
| Drug Descriptions |
i15.NKG2D.zeta NK cells are primary natural killer (NK) cells engineered to express a chimeric receptor consisting of NKG2D linked to the the T-cell receptor zeta chain, which may lead to killing of myeloid-derived suppressor cells in the tumor microenvironment and enhanced CAR-T cell activity (PMID: 30651290). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | NA |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| C7R-GD2.CAR-T cells + i15.NKG2D.zeta NK cells | C7R-GD2.CAR-T cells i15.NKG2D.zeta NK cells | 0 | 1 |
| i15.NKG2D.zeta NK cells | i15.NKG2D.zeta NK cells | 0 | 0 |
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