LRK-4189
Drug Detail

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Drug Name LRK-4189
Trade Name
Synonyms LRK4189|LRK 4189
Drug Descriptions

LRK-4189 targets PIP4K2C for degradation, which may lead to tumor cell death and activation of anti-tumor immune response (Journal for ImmunoTherapy of Cancer. 2025;13:1281).

DrugClasses
CAS Registry Number 3063346-83-5
NCIT ID NA

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Fluorouracil + Irinotecan + Leucovorin + LRK-4189 Fluorouracil Irinotecan LRK-4189 Leucovorin 0 1
Fluorouracil + Leucovorin + LRK-4189 + Oxaliplatin Fluorouracil LRK-4189 Leucovorin Oxaliplatin 0 1
LRK-4189 LRK-4189 0 1


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