iC9-GD2-CD28-OX40 T-cells
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| Drug Name | iC9-GD2-CD28-OX40 T-cells |
| Trade Name | |
| Synonyms | iC9-GD2|iC9 GD2 CD28 OX40 T-cells |
| Drug Descriptions |
iC9-GD2-CD28-OX40 T-cells comprises T-lymphocytes engineered to express a chimeric antigen receptor (CAR) that targets GD2 and contains CD28 and OX40 costimulatory domains, along with inducible Caspase-9, which potentially induces cytotoxicity against GD2-expressing tumor cells and inhibits tumor growth (PMID: 28602436). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C106123 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| iC9-GD2-CD28-OX40 T-cells | iC9-GD2-CD28-OX40 T-cells | 0 | 1 |
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