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Drug Name | Lestaurtinib |
Trade Name | |
Synonyms | CEP-701|KT-5555|A-154475|SP924 |
Drug Descriptions |
Lestaurtinib (CEP-701) inhibits JAK2, FLT3 and NTRK1-3, resulting in antiproliferative activity (PMID: 10415871, PMID: 17143529, PMID: 17442779, PMID: 17984313, PMID: 32441887). |
DrugClasses | CSF1R Inhibitor 28 FLT3 Inhibitor 69 JAK2 Inhibitor - ATP competitive 15 Trk Receptor Inhibitor (Pan) 32 |
CAS Registry Number | 111358-88-4 |
NCIT ID | C48402 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Cisplatin + Lestaurtinib | Cisplatin Lestaurtinib | 0 | 0 |
Lestaurtinib | Lestaurtinib | 37 | 0 |