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Drug Name | Duligotuzumab |
Trade Name | |
Synonyms | MEHD7945A |
Drug Descriptions |
Duligotuzumab (MEHD7945A) is a two-in-one antibody that inhibits both ERBB3 (HER3) and EGFR signaling, resulting in greater efficacy than monospecific HER antibodies against multiple tumor models (PMID: 22014573, PMID: 29506988). |
DrugClasses | EGFR Antibody 60 HER3 (ERBB3) Antibody 23 |
CAS Registry Number | 1312797-14-0 |
NCIT ID | C116628 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Afatinib + Duligotuzumab | Afatinib Duligotuzumab | 0 | 0 |
Cobimetinib + Duligotuzumab | Cobimetinib Duligotuzumab | 0 | 1 |
Duligotuzumab | Duligotuzumab | 0 | 2 |
Duligotuzumab + Radiotherapy | Duligotuzumab Radiotherapy | 0 | 0 |