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Drug Name | MM-151 |
Trade Name | |
Synonyms | |
Drug Descriptions |
MM-151 is a combination of three human monoclonal antibodies targeting distinct, non-overlapping epitopes of epidermal growth factor receptor (EGFR), thereby preventing the binding of ligands and inhibiting EGFR-ERK-mediated signaling (PMID: 26843189). |
DrugClasses | EGFR Antibody 60 |
CAS Registry Number | NA |
NCIT ID | C99899 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Fluorouracil + Irinotecan + Leucovorin + MM-151 | Fluorouracil Irinotecan Leucovorin MM-151 | 0 | 1 |
MM-151 | MM-151 | 0 | 2 |