Refametinib
Drug Detail
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| Drug Name | Refametinib |
| Trade Name | |
| Synonyms | BAY 869766|BAY 8697661|BAY-869766|BAY-8697661|BAY86-9766|RDEA-119|RDEA119 |
| Drug Descriptions |
Refametinib (BAY86-9766) is an inhibitor of MEK1 and MEK2, which prevents growth-factor mediated cell proliferation (PMID: 24204195, PMID: 32314268). |
| DrugClasses | MEK inhibitor (Pan) 27 MEK1 Inhibitor 27 MEK2 Inhibitor 25 |
| CAS Registry Number | 923032-37-5 |
| NCIT ID | C74059 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Copanlisib + Refametinib | Copanlisib Refametinib | 0 | 1 |
| Gemcitabine + Refametinib | Gemcitabine Refametinib | 0 | 0 |
| Refametinib | Refametinib | 4 | 1 |
| Refametinib + Regorafenib | Refametinib Regorafenib | 0 | 1 |
| Refametinib + Sorafenib | Refametinib Sorafenib | 1 | 1 |
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