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Drug Name | TAK-733 |
Trade Name | |
Synonyms | TAK733|REC-4881|REC4881|REC 4881 |
Drug Descriptions |
TAK-733 inhibits MEK1 and MEK2, preventing the activation of the RAS/RAF/MEK/ERK pathway, possibly inhibiting growth factor-mediated cell signaling and tumor cell proliferation (PMID: 26439693, PMID: 30396931). |
DrugClasses | MEK inhibitor (Pan) 26 MEK1 Inhibitor 26 MEK2 Inhibitor 24 |
CAS Registry Number | 1035555-63-5 |
NCIT ID | C84858 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Ganetespib + TAK-733 | Ganetespib TAK-733 | 1 | 0 |
TAK-733 | TAK-733 | 3 | 1 |