Triciribine
Drug Detail
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| Drug Name | Triciribine |
| Trade Name | |
| Synonyms | VQD-002|API-2 |
| Drug Descriptions |
Triciribine (API-2) is a purine analog that inhibits DNA synthesis, and blocks Akt phosphorylation, which may reduce proliferation and promote apoptosis in cancer cells (PMID: 21636709, PMID: 19422047). |
| DrugClasses | Akt Inhibitor (Pan) 22 |
| CAS Registry Number | 61966-08-3 |
| NCIT ID | C1262 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Carboplatin + Triciribine | Carboplatin Triciribine | 0 | 1 |
| Cytarabine + Triciribine | Cytarabine Triciribine | 0 | 1 |
| Doxorubicin + Triciribine | Doxorubicin Triciribine | 0 | 0 |
| NVP-TNKS656 + Triciribine | NVP-TNKS656 Triciribine | 1 | 0 |
| Paclitaxel + Triciribine | Paclitaxel Triciribine | 0 | 1 |
| Trametinib + Triciribine | Trametinib Triciribine | 0 | 0 |
| Triciribine | Triciribine | 0 | 0 |
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