Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Drug Name Triciribine
Trade Name
Synonyms VQD-002|API-2
Drug Descriptions

Triciribine (API-2) is a purine analog that inhibits DNA synthesis, and blocks Akt phosphorylation, which may reduce proliferation and promote apoptosis in cancer cells (PMID: 21636709, PMID: 19422047).

DrugClasses Akt Inhibitor (Pan) 21
CAS Registry Number 61966-08-3
NCIT ID C1262

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Carboplatin + Triciribine Carboplatin Triciribine 0 1
Cytarabine + Triciribine Cytarabine Triciribine 0 1
Doxorubicin + Triciribine Doxorubicin Triciribine 0 0
NVP-TNKS656 + Triciribine NVP-TNKS656 Triciribine 1 0
Paclitaxel + Triciribine Paclitaxel Triciribine 0 1
Trametinib + Triciribine Trametinib Triciribine 0 0
Triciribine Triciribine 0 0


Additional content available in CKB BOOST