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Drug Name | NVP-TNKS656 |
Trade Name | |
Synonyms | NVP656 |
Drug Descriptions |
NVP-TNKS656 is a small molecule that inhibits Tankyrase, resulting in decreased Beta-catenin signaling, and potentially leading to reduced tumor growth (PMID: 26224873, PMID: 30944457, PMID: 31897238). |
DrugClasses | Tankyrase Inhibitor 11 |
CAS Registry Number | 1419949-20-4 |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
NVP-TNKS656 | NVP-TNKS656 | 2 | 0 |
NVP-TNKS656 + Selumetinib | NVP-TNKS656 Selumetinib | 0 | 0 |
NVP-TNKS656 + Trametinib | NVP-TNKS656 Trametinib | 0 | 0 |
NVP-TNKS656 + Triciribine | NVP-TNKS656 Triciribine | 1 | 0 |