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Drug Name | Volasertib |
Trade Name | |
Synonyms | BI 6727|BI6727|BI-6727 |
Drug Descriptions |
Volasertib (BI 6727) inhibits polo-like kinase I (PLK1), resulting in cell cycle arrest and apoptosis in tumor cells (PMID: 27330107, PMID: 30782614, PMID: 32728610). |
DrugClasses | PLK1 Inhibitor 18 |
CAS Registry Number | 755038-65-4 |
NCIT ID | C79844 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Belinostat + Volasertib | Belinostat Volasertib | 0 | 1 |
Cytarabine + Idarubicin + Volasertib | Cytarabine Idarubicin Volasertib | 0 | 2 |
Cytarabine + Volasertib | Cytarabine Volasertib | 0 | 0 |
Decitabine + Volasertib | Decitabine Volasertib | 0 | 1 |
Eribulin + Volasertib | Eribulin Volasertib | 0 | 0 |
Fulvestrant + Palbociclib + Volasertib | Fulvestrant Palbociclib Volasertib | 0 | 0 |
Paclitaxel + Volasertib | Paclitaxel Volasertib | 0 | 0 |
RXDX-105 + Volasertib | RXDX-105 Volasertib | 0 | 0 |
Trametinib + Volasertib | Trametinib Volasertib | 0 | 0 |
Vincristine Sulfate + Volasertib | Vincristine Sulfate Volasertib | 0 | 1 |
Volasertib | Volasertib | 1 | 1 |