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Drug Name | Famitinib |
Trade Name | |
Synonyms | SHR1020|SHR-1020 |
Drug Descriptions |
Famitinib (SHR1020) is an analog of Sutent (sunitinib), a receptor tyrosine kinase (RTK) inhibitor, which inhibits receptor tyrosine kinases including c-Kit, VEGFR2/3, PDGFR-beta, RET, and FLT3 to reduce cell proliferation and tumor growth (PMID: 23126373, PMID: 30382933). |
DrugClasses | FLT3 Inhibitor 69 KIT Inhibitor 57 PDGFR-beta Inhibitor 14 RET Inhibitor 53 VEGFR2 Inhibitor 37 VEGFR3 Inhibitor 6 |
CAS Registry Number | 1044040-56-3 |
NCIT ID | C97512 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Camrelizumab + Famitinib + Nab-paclitaxel | Camrelizumab Famitinib Nab-paclitaxel | 0 | 0 |
Famitinib | Famitinib | 0 | 0 |
Famitinib + SHR-1701 | Famitinib SHR-1701 | 0 | 0 |