SNX-5422
Drug Detail
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| Drug Name | SNX-5422 |
| Trade Name | |
| Synonyms | PF-04929113|PF 04929113|SNX 5422 |
| Drug Descriptions |
SNX-5422 (PF-04929113) is the prodrug of the potent Hsp90 inhibitor SNX-2112, which has been shown to decrease activation Her-2, Akt, and ERK, inhibit tumor cell proliferation, and induce tumor cell apoptosis (PMID: 21349995, PMID: 18948577, PMID: 32468060). |
| DrugClasses | HSP90 Inhibitor 35 |
| CAS Registry Number | 908115-27-5 |
| NCIT ID | C141504 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Carboplatin + Paclitaxel + SNX-5422 | Carboplatin Paclitaxel SNX-5422 | 0 | 0 |
| Ibrutinib + SNX-5422 | Ibrutinib SNX-5422 | 0 | 2 |
| SNX-5422 | SNX-5422 | 0 | 5 |
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