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Drug Name Rociletinib
Trade Name
Synonyms CO1686|AVL-301|CNX-419|CS-1631|CO-1686
Drug Descriptions

Rociletinib (CO-1686) is a third-generation EGFR TKI inhibitor and inhibits mutant forms of EGFR including T790M (PMID: 24410791, PMID: 32528828).

DrugClasses EGFR Inhibitor 3rd gen 26
CAS Registry Number 1374640-70-6
NCIT ID C99905

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Afatinib + Rociletinib Afatinib Rociletinib 0 0
Atezolizumab + Rociletinib Atezolizumab Rociletinib 0 1
Bosutinib + Rociletinib Bosutinib Rociletinib 0 0
Cetuximab + Rociletinib Cetuximab Rociletinib 0 0
Crizotinib + Rociletinib Crizotinib Rociletinib 0 0
Dasatinib + Rociletinib Dasatinib Rociletinib 0 0
Rociletinib Rociletinib 0 7


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