Rigosertib Sodium
Drug Detail
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| Drug Name | Rigosertib Sodium |
| Trade Name | |
| Synonyms | ON 01910.Na|SyB L-1101 |
| Drug Descriptions |
Rigosertib (ON 01910.Na) inhibits polo-like kinase 1 (Plk1) and PI3K pathways, which induces selective G2/M arrest and apoptosis in tumor cells (PMID: 24777753). |
| DrugClasses | PI3K Inhibitor (Pan) 42 PLK1 Inhibitor 18 |
| CAS Registry Number | 592542-60-4 |
| NCIT ID | C71355 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Gemcitabine + Rigosertib Sodium | Gemcitabine Rigosertib Sodium | 0 | 0 |
| Palbociclib + Rigosertib Sodium | Palbociclib Rigosertib Sodium | 0 | 0 |
| Rigosertib Sodium | Rigosertib Sodium | 6 | 4 |
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