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Drug Name | AVX901 |
Trade Name | |
Synonyms | DUKE-002-VRP|HER2 ECDTM VRP|HER2 VRP|VRP-HER2|VRP-neu |
Drug Descriptions |
AVX901 is a virally based vaccine that infects cells and causes expression of a ERBB2 (HER2) ECD+TM protein that may activate the immune system to elicit a cytotoxic T-lymphocyte (CTL) response against ERBB2 (HER2)-expressing tumor cells (PMID: 29081765). |
DrugClasses | HER2 (ERBB2) Vaccine 14 |
CAS Registry Number | NA |
NCIT ID | C99903 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
AVX901 | AVX901 | 0 | 2 |
AVX901 + Pembrolizumab | AVX901 Pembrolizumab | 0 | 1 |