MRK-003
Drug Detail
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| Drug Name | MRK-003 |
| Trade Name | |
| Synonyms | |
| Drug Descriptions |
MRK-003 is a gamma-secretase inhibitor which inhibits Notch3 signaling and induces apoptosis in cancer cells (PMID: 17804716, PMID: 23887890). |
| DrugClasses | Gamma secretase inhibitor 13 |
| CAS Registry Number | 623165-93-5 |
| NCIT ID | NA |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| JQ1 + MRK-003 | JQ1 MRK-003 | 0 | 0 |
| MRK-003 | MRK-003 | 6 | 0 |
| MRK-003 + Paclitaxel | MRK-003 Paclitaxel | 0 | 0 |
| MRK-003 + Radiotherapy | MRK-003 Radiotherapy | 0 | 0 |
| MRK-003 + SCH772984 | MRK-003 SCH772984 | 0 | 0 |
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