Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Drug Name | MRK-003 |
Trade Name | |
Synonyms | |
Drug Descriptions |
MRK-003 is a gamma-secretase inhibitor which inhibits Notch3 signaling and induces apoptosis in cancer cells (PMID: 17804716, PMID: 23887890). |
DrugClasses | Gamma secretase inhibitor 13 |
CAS Registry Number | 623165-93-5 |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
JQ1 + MRK-003 | JQ1 MRK-003 | 0 | 0 |
MRK-003 | MRK-003 | 6 | 0 |
MRK-003 + Paclitaxel | MRK-003 Paclitaxel | 0 | 0 |
MRK-003 + Radiotherapy | MRK-003 Radiotherapy | 0 | 0 |
MRK-003 + SCH772984 | MRK-003 SCH772984 | 0 | 0 |