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Drug Name | Conatumumab |
Trade Name | |
Synonyms | AMG 655|AMG-655|AMG655 |
Drug Descriptions |
Conatumumab (AMG 655) is a monoclonal antibody that binds to and activates the TRAIL receptor 2 (TR-2), initiating caspase activation and inducing tumor cell apoptosis (PMID: 24816908). |
DrugClasses | |
CAS Registry Number | 896731-82-1 |
NCIT ID | C71015 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Conatumumab | Conatumumab | 0 | 2 |
Conatumumab + Ganitumab | Conatumumab Ganitumab | 0 | 0 |