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| Drug Name | Ganitumab |
| Trade Name | |
| Synonyms | AMG-479 |
| Drug Descriptions |
Ganitumab (AMG-479) is a recombinant antibody that binds to and inhibits IGF-1R. Inhibition of IGF-1R prevents activation of the downstream PI3K/Akt pathway, which may inhibit proliferation and induce apoptosis of tumor cells (NCI Drug Dictionary). |
| DrugClasses | IGF-1R Inhibitor 17 |
| CAS Registry Number | 905703-97-1 |
| NCIT ID | C71531 |
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