HMN-214
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| Drug Name | HMN-214 |
| Trade Name | |
| Synonyms | |
| Drug Descriptions |
HMN-214 is a prodrug of the active agent HMN-176, which interferes with the location of PLK1, leading to cell cycle arrest, destruction of the spindle polar bodies, and DNA fragmentation (PMID: 19474163, PMID: 16951237). |
| DrugClasses | PLK1 Inhibitor 18 |
| CAS Registry Number | 173529-46-9 |
| NCIT ID | NA |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| HMN-214 | HMN-214 | 0 | 0 |
| HMN-214 + Palbociclib | HMN-214 Palbociclib | 1 | 0 |
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