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Drug Name EC1456
Trade Name
Synonyms
Drug Descriptions

EC1456 is a small molecule drug comprised of folate (vitamin B9) linked to the cytotoxic agent, tubulysin B hydrazide, which is internalized by folate receptor-expressing tumor cells to inhibit microtubule polymerization thereby, inhibiting cell cycle progression and inducing apoptosis (PMID: 29895863, PMID: 32728172).

DrugClasses
CAS Registry Number NA
NCIT ID C113176

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Therapy Name Drugs Efficacy Evidence Clinical Trials
EC1456 EC1456 0 1


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