rAD-p53
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| Drug Name | rAD-p53 |
| Trade Name | |
| Synonyms | Gendicine|Genkaxin |
| Drug Descriptions |
Gendicine (rAD-p53) is a replication-defective adenoviral vector encoding wild-type TP53, which induces tumor cells to produce wild-type Tp53 and potentially induce apoptosis. Gendicine may also stimulate a cytotoxic T-lymphocyte immune response against tumor cells, and activate natural killer cells (PMID: 29338444, PMID: 32013587, PMID: 30618300). |
| DrugClasses | p53 Gene Therapy 4 |
| CAS Registry Number | NA |
| NCIT ID | C85485 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| rAD-p53 | rAD-p53 | 0 | 1 |
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