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Therapy Name | rAD-p53 |
Synonyms | |
Therapy Description |
Gendicine (rAD-p53) is a replication-defective adenoviral vector encoding wild-type TP53, which induces tumor cells to produce wild-type Tp53 and potentially induce apoptosis. Gendicine may also stimulate a cytotoxic T-lymphocyte immune response against tumor cells, and activate natural killer cells (PMID: 29338444, PMID: 32013587, PMID: 30618300). |