ZM336372
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| Drug Name | ZM336372 |
| Trade Name | |
| Synonyms | ZM 336372|ZM-336372 |
| Drug Descriptions |
ZM336372 is a small molecule RAF1 inhibitor that paradoxically causes RAF1 activation through a putative feedback mechanism, resulting in decreased proliferation and cell cycle inhibition in carcinoid tumor cells (PMID: 20031160, PMID: 15956248). |
| DrugClasses | CRAF Inhibitor 12 |
| CAS Registry Number | 208260-29-1 |
| NCIT ID | NA |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Vemurafenib + ZM336372 | Vemurafenib ZM336372 | 1 | 0 |
| ZM336372 | ZM336372 | 1 | 0 |
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