Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Drug Name | Tagraxofusp-erzs |
Trade Name | Elzonris |
Synonyms | Tagraxofusp|SL-401|DT3881L3|DT-3881L3 |
Drug Descriptions |
Elzonris (Tagraxofusp-erzs) is a fusion protein consists of human interleukin 3 (IL3) and the first 388 amino acids of diphtheria toxin [DT(388)], which binds to IL3 receptors and subsequently inhibits protein synthesis, leading to cell death (PMID: 28479592). Elzonris (tagraxofusp-erzs) is FDA approved for use in pediatric and adult patients with blastic plasmacytoid dendritic cell neoplasm (FDA.gov). |
DrugClasses | |
CAS Registry Number | 2055491-00-2 |
NCIT ID | C64769 |