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Drug Name Filgrastim
Trade Name Neupogen
Synonyms G-CSF
Drug Descriptions

Neupogen (filgrastim) is a recombinant analog of granulocyte colony-stimulating factor (G-CSF) isoform B, which binds and activates G-CSF receptors modulating neutrophilic granulocyte progenitor activity, production, and differentiation (NCI Drug Dictionary).

DrugClasses
CAS Registry Number 121181-53-1
NCIT ID C1474

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Ad5-survivin-transduced autologous DC vaccine + Filgrastim + PCV13 vaccine Ad5-survivin-transduced autologous DC vaccine Filgrastim PCV13 vaccine 0 1
Aldoxorubicin + Cisplatin + Filgrastim + Methotrexate + Vinblastine Aldoxorubicin Cisplatin Filgrastim Methotrexate Vinblastine 0 1
anti-thymocyte globulin + Cyclophosphamide + Filgrastim + Fludarabine + Melphalan + Mesna + Thiotepa Cyclophosphamide Filgrastim Fludarabine Melphalan Mesna Thiotepa anti-thymocyte globulin 0 1
Atezolizumab + Cyclophosphamide + Doxorubicin + Filgrastim + Tiragolumab Atezolizumab Cyclophosphamide Doxorubicin Filgrastim Tiragolumab 0 1
Azacitidine + Cytarabine + Filgrastim + Fludarabine + Venetoclax + Vorinostat Azacitidine Cytarabine Filgrastim Fludarabine Venetoclax Vorinostat 0 1
Basiliximab + Carmustine + Cytarabine + Etoposide + Filgrastim + Yttrium Y 90 Basiliximab Basiliximab Carmustine Cytarabine Etoposide Filgrastim Yttrium Y 90 Basiliximab 0 1
BKT140 + Filgrastim BKT140 Filgrastim 0 1
Bortezomib + Cyclophosphamide + Filgrastim Bortezomib Cyclophosphamide Filgrastim 0 1
Bortezomib + Filgrastim Bortezomib Filgrastim 0 2
Brentuximab vedotin + Dacarbazine + Doxorubicin + Filgrastim + Vinblastine Brentuximab vedotin Dacarbazine Doxorubicin Filgrastim Vinblastine 0 2
Busulfan + Filgrastim + Fludarabine + Melphalan + MGTA-456 + Mycophenolate mofetil + Tacrolimus Busulfan Filgrastim Fludarabine MGTA-456 Melphalan Mycophenolate mofetil Tacrolimus 0 1
Cabozantinib + Cyclophosphamide + Filgrastim + Topotecan Cabozantinib Cyclophosphamide Filgrastim Topotecan 0 1
Carboplatin + Cisplatin + Cyclophosphamide + Etoposide + Filgrastim Carboplatin Cisplatin Cyclophosphamide Etoposide Filgrastim 0 1
Carboplatin + Cyclophosphamide + Etoposide + Filgrastim Carboplatin Cyclophosphamide Etoposide Filgrastim 0 1
Carmustine + Cytarabine + Etoposide + Filgrastim + Lenalidomide + Melphalan + Rituximab Carmustine Cytarabine Etoposide Filgrastim Lenalidomide Melphalan Rituximab 0 1
Carmustine + Filgrastim + O6-benzylguanine + Temozolomide Carmustine Filgrastim O6-benzylguanine Temozolomide 0 1
Carmustine + Filgrastim + Plerixafor + Temozolomide Carmustine Filgrastim Plerixafor Temozolomide 0 1
CD45RA-depleted donor lymphocytes + Cyclophosphamide + Filgrastim + Fludarabine + Melphalan + Tacrolimus CD45RA-depleted donor lymphocytes Cyclophosphamide Filgrastim Fludarabine Melphalan Tacrolimus 0 0
Cisplatin + Cytarabine + Dexamethasone + Filgrastim + Rituximab Cisplatin Cytarabine Dexamethasone Filgrastim Rituximab 0 1
Cisplatin + Filgrastim + Fluorouracil + Hydroxyurea + Paclitaxel Cisplatin Filgrastim Fluorouracil Hydroxyurea Paclitaxel 0 1
Cladribine + Cytarabine + Filgrastim Cladribine Cytarabine Filgrastim 0 2
Cladribine + Cytarabine + Filgrastim + Gemtuzumab ozogamicin Cladribine Cytarabine Filgrastim Gemtuzumab ozogamicin 0 1
Cladribine + Cytarabine + Filgrastim + Gemtuzumab ozogamicin + Mitoxantrone Cladribine Cytarabine Filgrastim Gemtuzumab ozogamicin Mitoxantrone 0 1
Cladribine + Cytarabine + Filgrastim + Gilteritinib + Mitoxantrone Cladribine Cytarabine Filgrastim Gilteritinib Mitoxantrone 0 1
Cladribine + Cytarabine + Filgrastim + Idarubicin Cladribine Cytarabine Filgrastim Idarubicin 0 1
Cladribine + Cytarabine + Filgrastim + Mitoxantrone Cladribine Cytarabine Filgrastim Mitoxantrone 0 3
Cladribine + Cytarabine + Filgrastim + Mitoxantrone + Navitoclax + Venetoclax Cladribine Cytarabine Filgrastim Mitoxantrone Navitoclax Venetoclax 0 1
Cladribine + Cytarabine + Filgrastim + Mitoxantrone + Venetoclax Cladribine Cytarabine Filgrastim Mitoxantrone Venetoclax 0 0
CPX-351 + Cytarabine + Filgrastim + Fludarabine CPX-351 Cytarabine Filgrastim Fludarabine 0 1
Crenolanib + Cytarabine + Filgrastim + Fludarabine + Idarubicin + Mitoxantrone Crenolanib Cytarabine Filgrastim Fludarabine Idarubicin Mitoxantrone 0 1
Cyclophosphamide + Cytarabine + Dexamethasone + DS-1594b + Filgrastim + Mesna + Methotrexate + Vincristine Sulfate Cyclophosphamide Cytarabine DS-1594b Dexamethasone Filgrastim Mesna Methotrexate Vincristine Sulfate 0 1
Cyclophosphamide + Cytarabine + Doxorubicin + Etoposide + Filgrastim + Ifosfamide + Leucovorin + Mesna + Methotrexate + Rituximab + Vincristine Sulfate Cyclophosphamide Cytarabine Doxorubicin Etoposide Filgrastim Ifosfamide Leucovorin Mesna Methotrexate Rituximab Vincristine Sulfate 0 1
Cyclophosphamide + Doxorubicin + Etoposide + Filgrastim + Ibrutinib + Pegfilgrastim + Prednisone + Rituximab + Vincristine Sulfate Cyclophosphamide Doxorubicin Etoposide Filgrastim Ibrutinib Pegfilgrastim Prednisone Rituximab Vincristine Sulfate 0 1
Cyclophosphamide + Doxorubicin + Etoposide + Filgrastim + Nivolumab + Prednisone + Rituximab + Vincristine Sulfate Cyclophosphamide Doxorubicin Etoposide Filgrastim Nivolumab Prednisone Rituximab Vincristine Sulfate 0 1
Cyclophosphamide + Doxorubicin + Etoposide + Filgrastim + Polatuzumab vedotin-piiq + Prednisone + Rituximab Cyclophosphamide Doxorubicin Etoposide Filgrastim Polatuzumab vedotin-piiq Prednisone Rituximab 0 1
Cyclophosphamide + Doxorubicin + Etoposide + Filgrastim + Prednisone + Rituximab + Vincristine Sulfate Cyclophosphamide Doxorubicin Etoposide Filgrastim Prednisone Rituximab Vincristine Sulfate 0 2
Cyclophosphamide + Filgrastim + Fludarabine + MGTA-456 + Mycophenolate mofetil + Tacrolimus Cyclophosphamide Filgrastim Fludarabine MGTA-456 Mycophenolate mofetil Tacrolimus 0 1
Cyclophosphamide + Filgrastim + Mycophenolate mofetil + Sirolimus + Tacrolimus Cyclophosphamide Filgrastim Mycophenolate mofetil Sirolimus Tacrolimus 0 1
Cyclophosphamide + Filgrastim + Mycophenolate mofetil + Tacrolimus + Testosterone cypionate Cyclophosphamide Filgrastim Mycophenolate mofetil Tacrolimus Testosterone cypionate 0 1
Cyclophosphamide + Filgrastim + Simvastatin + Topotecan Cyclophosphamide Filgrastim Simvastatin Topotecan 0 1
Cytarabine + Dasatinib + Dexamethasone + Filgrastim + Fludarabine + Methotrexate Cytarabine Dasatinib Dexamethasone Filgrastim Fludarabine Methotrexate 0 0
Cytarabine + Dexamethasone + Filgrastim + Methotrexate + Nilotinib + Vincristine Sulfate Cytarabine Dexamethasone Filgrastim Methotrexate Nilotinib Vincristine Sulfate 0 1
Cytarabine + DS-1594b + Filgrastim + Leucovorin + Methotrexate Cytarabine DS-1594b Filgrastim Leucovorin Methotrexate 0 1
Cytarabine + DS-1594b + Filgrastim + Leucovorin + Methotrexate + Rituximab Cytarabine DS-1594b Filgrastim Leucovorin Methotrexate Rituximab 0 1
Cytarabine + Filgrastim + Fludarabine Cytarabine Filgrastim Fludarabine 0 2
Cytarabine + Filgrastim + Fludarabine + Gemtuzumab ozogamicin Cytarabine Filgrastim Fludarabine Gemtuzumab ozogamicin 0 1
Cytarabine + Filgrastim + Fludarabine + Gemtuzumab ozogamicin + Idarubicin Cytarabine Filgrastim Fludarabine Gemtuzumab ozogamicin Idarubicin 0 1
Cytarabine + Filgrastim + Fludarabine + Gilteritinib Cytarabine Filgrastim Fludarabine Gilteritinib 0 1
Cytarabine + Filgrastim + Fludarabine + Idarubicin Cytarabine Filgrastim Fludarabine Idarubicin 0 1
Cytarabine + Filgrastim + Fludarabine + Idarubicin + Mitoxantrone Cytarabine Filgrastim Fludarabine Idarubicin Mitoxantrone 0 1
Cytarabine + Filgrastim + Fludarabine + Idarubicin + Quizartinib Cytarabine Filgrastim Fludarabine Idarubicin Quizartinib 0 0
Cytarabine + Filgrastim + Fludarabine + Idarubicin + Venetoclax Cytarabine Filgrastim Fludarabine Idarubicin Venetoclax 0 1
Cytarabine + Filgrastim + Fludarabine + Idarubicin + Ziftomenib Cytarabine Filgrastim Fludarabine Idarubicin Ziftomenib 0 1
Cytarabine + Filgrastim + Fludarabine + Ivosidenib Cytarabine Filgrastim Fludarabine Ivosidenib 0 1
Cytarabine + Filgrastim + Fludarabine + Methotrexate + Selinexor + Venetoclax Cytarabine Filgrastim Fludarabine Methotrexate Selinexor Venetoclax 0 1
Cytarabine + Filgrastim + Fludarabine + Venetoclax Cytarabine Filgrastim Fludarabine Venetoclax 0 1
Cytarabine + Filgrastim + GDC-0575 Cytarabine Filgrastim GDC-0575 0 0
Cytarabine + Filgrastim + Methotrexate + Rituximab + Tagraxofusp-erzs Cytarabine Filgrastim Methotrexate Rituximab Tagraxofusp-erzs 0 1
Dexamethasone + Filgrastim + Palifermin + Rituximab Dexamethasone Filgrastim Palifermin Rituximab 0 1
Docetaxel + Filgrastim + Prednisone + Ribociclib Docetaxel Filgrastim Prednisone Ribociclib 0 1
Etoposide + Filgrastim + Plerixafor Etoposide Filgrastim Plerixafor 0 1
Filgrastim Filgrastim 0 45
Filgrastim + Gemcitabine + Pegfilgrastim + Ribociclib Filgrastim Gemcitabine Pegfilgrastim Ribociclib 0 0
Filgrastim + Gemcitabine + Ribociclib Filgrastim Gemcitabine Ribociclib 0 1
Filgrastim + Idarubicin Filgrastim Idarubicin 0 1
Filgrastim + Methotrexate Filgrastim Methotrexate 0 1
Filgrastim + Methotrexate + Rituximab Filgrastim Methotrexate Rituximab 0 1
Filgrastim + mRNA plus lysate-loaded dendritic cell vaccine + Paclitaxel + Peg-interferon alfa-2a Filgrastim Paclitaxel Peg-interferon alfa-2a mRNA plus lysate-loaded dendritic cell vaccine 0 1
Filgrastim + Mycophenolate mofetil + Tacrolimus Filgrastim Mycophenolate mofetil Tacrolimus 0 2
Filgrastim + Plerixafor Filgrastim Plerixafor 0 3


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