GDC-0575
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| Drug Name | GDC-0575 |
| Trade Name | |
| Synonyms | ARRY-575|RG7741 |
| Drug Descriptions |
GDC-0575 selectively inhibits CHK1, which potentially results in increased response to chemotherapeutic agents (PMID: 29162833, PMID: 29788155). |
| DrugClasses | CHK1 Inhibitor 18 |
| CAS Registry Number | 1196541-47-5 |
| NCIT ID | C116845 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Cytarabine + Filgrastim + GDC-0575 | Cytarabine Filgrastim GDC-0575 | 0 | 0 |
| Cytarabine + GDC-0575 | Cytarabine GDC-0575 | 0 | 0 |
| GDC-0575 | GDC-0575 | 0 | 1 |
| GDC-0575 + Gemcitabine | GDC-0575 Gemcitabine | 2 | 1 |
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