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Drug Name | GDC-0575 |
Trade Name | |
Synonyms | ARRY-575|RG7741 |
Drug Descriptions |
GDC-0575 selectively inhibits CHK1, which potentially results in increased response to chemotherapeutic agents (PMID: 29162833, PMID: 29788155). |
DrugClasses | CHK1 Inhibitor 18 |
CAS Registry Number | 1196541-47-5 |
NCIT ID | C116845 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Cytarabine + Filgrastim + GDC-0575 | Cytarabine Filgrastim GDC-0575 | 0 | 0 |
Cytarabine + GDC-0575 | Cytarabine GDC-0575 | 0 | 0 |
GDC-0575 | GDC-0575 | 0 | 1 |
GDC-0575 + Gemcitabine | GDC-0575 Gemcitabine | 4 | 1 |