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Drug Name | CDX-3379 |
Trade Name | |
Synonyms | CDX3379|MEDI3379|KTN3379 |
Drug Descriptions |
CDX-3379 (KTN3379) is a monoclonal antibody that targets ERBB3 (HER3) and prevents ligand binding and downstream signaling, potentially leads to inhibition of tumor cell growth (PMID: 31308059). |
DrugClasses | HER3 (ERBB3) Antibody 23 |
CAS Registry Number | 2070921-00-3 |
NCIT ID | C113333 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
CDX-3379 | CDX-3379 | 0 | 2 |
CDX-3379 + Cetuximab | CDX-3379 Cetuximab | 0 | 2 |
CDX-3379 + Erlotinib | CDX-3379 Erlotinib | 0 | 1 |
CDX-3379 + Trametinib | CDX-3379 Trametinib | 0 | 1 |
CDX-3379 + Trastuzumab | CDX-3379 Trastuzumab | 0 | 1 |
CDX-3379 + Vemurafenib | CDX-3379 Vemurafenib | 0 | 2 |