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Drug Name | ICG-001 |
Trade Name | |
Synonyms | ICG001|ICG 001 |
Drug Descriptions |
ICG-001 disrupts the interaction of CTNNB1 and c-AMP response element-binding protein, thereby preventing downstream CTNNB1 signaling to promote apoptosis (PMID: 15314234, PMID: 29332125, PMID: 32642722). |
DrugClasses | CTNNB1 Inhibitor 27 |
CAS Registry Number | 780757-88-2 |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
HER2 CAR-T cells + ICG-001 | HER2 CAR-T cells ICG-001 | 0 | 0 |
ICG-001 | ICG-001 | 1 | 0 |
ICG-001 + Verteporfin | ICG-001 Verteporfin | 0 | 0 |