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Drug Name ICG-001
Trade Name
Synonyms ICG001|ICG 001
Drug Descriptions

ICG-001 disrupts the interaction of CTNNB1 and c-AMP response element-binding protein, thereby preventing downstream CTNNB1 signaling to promote apoptosis (PMID: 15314234, PMID: 29332125, PMID: 32642722).

DrugClasses CTNNB1 Inhibitor 27
CAS Registry Number 780757-88-2
NCIT ID NA

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Therapy Name Drugs Efficacy Evidence Clinical Trials
HER2 CAR-T cells + ICG-001 HER2 CAR-T cells ICG-001 0 0
ICG-001 ICG-001 1 0
ICG-001 + Verteporfin ICG-001 Verteporfin 0 0


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