Spebrutinib
Drug Detail
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| Drug Name | Spebrutinib |
| Trade Name | |
| Synonyms | AVL-292|CC-292 |
| Drug Descriptions |
Spebrutinib (CC-292) is a covalent inhibitor of Btk that decreases Btk kinase activity and activation of downstream signaling, resulting in reduced B-cell proliferation (PMID: 24518207, PMID: 31721017). |
| DrugClasses | BTK inhibitor 38 |
| CAS Registry Number | 1202757-89-8 |
| NCIT ID | C97037 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| CC-122 + Spebrutinib | CC-122 Spebrutinib | 0 | 1 |
| Onatasertib + Spebrutinib | Onatasertib Spebrutinib | 0 | 1 |
| Spebrutinib | Spebrutinib | 0 | 0 |
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