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Drug Name | Spebrutinib |
Trade Name | |
Synonyms | AVL-292|CC-292 |
Drug Descriptions |
Spebrutinib (CC-292) is a covalent inhibitor of Btk that decreases Btk kinase activity and activation of downstream signaling, resulting in reduced B-cell proliferation (PMID: 24518207, PMID: 31721017). |
DrugClasses | BTK inhibitor 37 |
CAS Registry Number | 1202757-89-8 |
NCIT ID | C97037 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
CC-122 + Spebrutinib | CC-122 Spebrutinib | 0 | 1 |
Onatasertib + Spebrutinib | Onatasertib Spebrutinib | 0 | 1 |
Spebrutinib | Spebrutinib | 0 | 0 |