Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Drug Name | TAE684 |
Trade Name | |
Synonyms | NVP-TAE684|TAE-684|TAE 684 |
Drug Descriptions |
TAE684 inhibits Fes, Alk, and Tnk2 (Ack1) kinase activity, which may result in decreased proliferation of tumor cells (PMID: 17185414, PMID: 25699576, PMID: 22520759, PMID: 32344689). |
DrugClasses | ALK Inhibitor 32 TNK2 Inhibitor 6 |
CAS Registry Number | 761439-42-3 |
NCIT ID | C171615 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Idasanutlin + TAE684 | Idasanutlin TAE684 | 3 | 0 |
TAE684 | TAE684 | 9 | 0 |