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Drug Name | Galunisertib |
Trade Name | |
Synonyms | LY2157299|LY-2157299 |
Drug Descriptions |
Galunisertib (LY2157299) is a TGFBR1 antagonist, which inhibits downstream signaling and may suppress tumor growth (PMID: 18039567, PMID: 32210440). |
DrugClasses | TGFBR1 inhibitor 16 |
CAS Registry Number | 700874-72-2 |
NCIT ID | C116891 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Abemaciclib + Galunisertib | Abemaciclib Galunisertib | 0 | 1 |
Capecitabine + Galunisertib | Capecitabine Galunisertib | 0 | 2 |
Carboplatin + Galunisertib + Paclitaxel | Carboplatin Galunisertib Paclitaxel | 0 | 1 |
Durvalumab + Galunisertib | Durvalumab Galunisertib | 0 | 1 |
Fluorouracil + Galunisertib | Fluorouracil Galunisertib | 0 | 1 |
Galunisertib | Galunisertib | 0 | 6 |
Galunisertib + Paclitaxel | Galunisertib Paclitaxel | 0 | 1 |
Galunisertib + Sorafenib | Galunisertib Sorafenib | 0 | 1 |