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Drug Name | PLX7486 |
Trade Name | |
Synonyms | PLX 7486|PLX-7486 |
Drug Descriptions |
PLX7486 binds to and inhibits CSF1R, TRKA, TRKB, and TRKC, which potentially results in decreased tumor cell proliferation (PMID: 28174090). |
DrugClasses | CSF1R Inhibitor 28 Trk Receptor Inhibitor (Pan) 32 |
CAS Registry Number | NA |
NCIT ID | C105804 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
PLX7486 | PLX7486 | 0 | 1 |
PLX7486 + unspecified CTLA4 antibody | PLX7486 unspecified CTLA4 antibody | 0 | 0 |
PLX7486 + unspecified PD-1 antibody | PLX7486 unspecified PD-1 antibody | 0 | 0 |