Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Drug Name Talimogene laherparepvec
Trade Name Imlygic
Synonyms OncoVEX GM-CSF|T-VEC
Drug Descriptions

Imlygic (talimogene laherparepvec) is a GM-CSF expressing herpes simplex type-1 virus (HSV-1) that selectively infects and lyses tumor cells, and potentially induces a cytotoxic immune response against tumor cells (PMID: 25777572). Imlygic (talimogene laherparepvec) is FDA approved for use in patients with recurrent melanoma (FDA.gov).

DrugClasses
CAS Registry Number 1187560-31-1
NCIT ID C61314

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Anastrozole + Talimogene laherparepvec Anastrozole Talimogene laherparepvec 0 1
Atezolizumab + Talimogene laherparepvec Atezolizumab Talimogene laherparepvec 0 2
Capecitabine + Fluorouracil + Oxaliplatin + Talimogene laherparepvec Capecitabine Fluorouracil Oxaliplatin Talimogene laherparepvec 0 1
Carboplatin + Gemcitabine + Talimogene laherparepvec Carboplatin Gemcitabine Talimogene laherparepvec 0 1
Dabrafenib + Talimogene laherparepvec + Trametinib Dabrafenib Talimogene laherparepvec Trametinib 0 2
Exemestane + Talimogene laherparepvec Exemestane Talimogene laherparepvec 0 1
Fulvestrant + Talimogene laherparepvec Fulvestrant Talimogene laherparepvec 0 1
Ipilimumab + Nivolumab + Talimogene laherparepvec Ipilimumab Nivolumab Talimogene laherparepvec 0 1
Letrozole + Talimogene laherparepvec Letrozole Talimogene laherparepvec 0 1
Nab-paclitaxel + Talimogene laherparepvec Nab-paclitaxel Talimogene laherparepvec 0 1
Nivolumab + Talimogene laherparepvec Nivolumab Talimogene laherparepvec 0 2
Nivolumab + Talimogene laherparepvec + Trabectedin Nivolumab Talimogene laherparepvec Trabectedin 0 1
Paclitaxel + Talimogene laherparepvec Paclitaxel Talimogene laherparepvec 0 2
Panitumumab + Talimogene laherparepvec Panitumumab Talimogene laherparepvec 0 1
Pembrolizumab + Talimogene laherparepvec Pembrolizumab Talimogene laherparepvec 0 6
Talimogene laherparepvec Talimogene laherparepvec 0 14
Talimogene laherparepvec + Tamoxifen Talimogene laherparepvec Tamoxifen 0 1


Additional content available in CKB BOOST